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Article

Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2012

Marcucci Guido, Metzeler Klaus H, Schwind Sebastian, Becker Heiko, Maharry Kati, Mrózek Krzysztof, Radmacher Michael D, Kohlschmidt Jessica, Nicolet Deedra, Whitman Susan P, Wu Yue-Zhong, Powell Bayard L, Carter Thomas H, Kolitz Jonathan E, Wetzler Meir, Carroll Andrew J, Baer Maria R, Moore Joseph O, Caligiuri Michael A, Larson Richard A, Bloomfield Clara D

Abstract excerpt

PURPOSE: To determine the frequency of DNMT3A mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and microRNA-expression signatures in primary cytogenetically normal acute myeloid leukemia (CN-AML). PATIENTS AND METHODS: Four hundred fi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22291079
DOI: 10.1200/JCO.2011.39.2092
PMCID: PMC3295550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22291079-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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