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Article

Hypoxia regulation of ATP13A2 (PARK9) gene transcription

31 Jan 2012

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative disorders with a variable combination of motor and non-motor symptoms. Mutations in several genes including ATP13A2 (PARK9) are reported to be associated with PD. The underlying mechanism of PD is not well defined, however, both genetic and environmental causes contribute to it. ATP13A2 gene locates in chromosome 1 and contains 29 exons encoding...

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PMID: 22288903
DOI: 10.1111/j.1471-4159.2012.07676.x

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