Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression.

doi:10.1016/j.phymed.2016.08.004

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Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression.

Phytomedicine : international journal of phytotherapy and phytopharmacology - 15 Nov 2016

Chen Chiung-Mei, Chen I-Cheng, Chen Ying-Lin, Lin Te-Hsien, Chen Wan-Ling, Chao Chih-Ying, Wu Yih-Ru, Lu Yeah-Ting, Lee Cheng-Yu, Chien Hong-Chi, Chen Ting-Shou, Lee-Chen Guey-Jen, Lee Chi-Mei

Abstract excerpt

BACKGROUND: The F-box protein 7 (FBXO7) mutations have been identified in families with early-onset parkinsonism and pyramidal tract signs, and designated as PARK15. In addition, FBXO7 mutations were found in typical and young onset Parkinson's disease (PD). Evidence has also shown that FBXO7 plays an important role in the development of dopaminergic neurons and increased stability and overexpression of FBXO7 may...

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Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression.

Abstract excerpt

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