Article
Differentiation of African components of ancestry to stratify groups in a case-control study of a Brazilian urban population.
Genetic testing and molecular biomarkers - 1 Jun 2012
Silbiger Vivian N, Hirata Mario H, Luchessi Andre D, Genvigir Fabiana D V, Cerda Alvaro, Rodrigues Alice C, Willrich Maria A V, Arazi Simone S, Dorea Egidio L, Bernik Marcia M S, Faludi Andre A, Bertolami Marcelo C, Santos Carla, Carracedo Angel, Salas Antonio, Freire Ana, Lareu Maria Victoria, Phillips Christopher, Porras-Hurtado Liliana, Fondevila Manuel, Hirata Rosario D C
Abstract excerpt
BACKGROUND: Balancing the subject composition of case and control groups to create homogenous ancestries between each group is essential for medical association studies. METHODS: We explored the applicability of single-tube 34-plex ancestry informative markers (AIM) single nucleotide polymorphisms (SNPs) to estimate the African Component of Ancestry (ACA) to design a future case-control association study of a...
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