A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives.

doi:10.1093/jac/26.3.307

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Article

A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives.

The Journal of antimicrobial chemotherapy - 1 Sept 1990

Cannon M, Harford S, Davies J

Abstract excerpt

Chloramphenicol, thiamphenicol and three fluorinated derivatives, Sch 24893, Sch 25298 and Sch 25393, were studied with respect to inhibition of the growth of selected bacterial strains and cell-free translation systems. Thiamphenicol was the least potent inhibitor in the former experiments, but...

Topics

Chloramphenicol
Chloramphenicol O-Acetyltransferase
Chloramphenicol Resistance
Escherichia coli
Humans
Mutation
Peptidyl Transferases
Protein Biosynthesis
Ribosomes
Saccharomyces cerevisiae
Thiamphenicol

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