Article
Clinical isolate of a porinless Salmonella typhi resistant to high levels of chloramphenicol.
Antimicrobial agents and chemotherapy - 1 Sept 1990
Toro C S, Lobos S R, Calderón I, Rodríguez M, Mora G C
Abstract excerpt
We studied a clinical isolate of Salmonella typhi (strain 1895) characterized by resistance to 200 micrograms of chloramphenicol per ml despite the absence of chloramphenicol-inactivating activity. The outer membrane protein profile analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated a deficiency of one of the major protein species which may serve as a porin for entry of...
Topics
- Bacterial Outer Membrane Proteins
- Cell Division
- Chloramphenicol
- Chloramphenicol Resistance
- Conjugation, Genetic
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Mutation
- Plasmids
- Ribosomes