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Article

ATP13A2 (PARK9) polymorphisms influence the neurotoxic effects of manganese.

Neurotoxicology - 1 Aug 2012

Rentschler Gerda, Covolo Loredana, Haddad Amelia Ahmadi, Lucchini Roberto G, Zoni Silvia, Broberg Karin

Abstract excerpt

INTRODUCTION: A higher prevalence of individuals affected by Parkinsonism was found in Valcamonica, Italy. This may be related to ferro-alloy smelters in the area, releasing manganese (Mn) in the air, soil and water for about a century. There exists individual susceptibility for Mn neurotoxicity. AIM: To analyse how polymorphism in genes regulating Mn metabolism and toxicity can modify neurophysiological effects...

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Identifiers

PMID: 22285144
DOI: 10.1016/j.neuro.2012.01.007
PMCID: PMC3997180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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