Article
Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis.
BMC medical genetics - 27 Jan 2012
Knüppel Sven, Esparza-Gordillo Jorge, Marenholz Ingo, Holzhütter Hermann-Georg, Bauerfeind Anja, Ruether Andreas, Weidinger Stephan, Lee Young-Ae, Rohde Klaus
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) provide an increasing number of single nucleotide polymorphisms (SNPs) associated with diseases. Our aim is to exploit those closely spaced SNPs in candidate regions for a deeper analysis of association beyond single SNP analysis, combining the c...
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