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Article

Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carcinoma: a meta-analysis.

Scientific reports - 29 Jan 2015

Meng Fan-dong, Ma Ping, Sui Cheng-guang, Tian Xin, Jiang You-hong

Abstract excerpt

Cytochrome P450 1A1 (CYP1A1) usually metabolizes carcinogens to their inactive derivatives but occasionally converts the chemicals to more potent carcinogens. To date, many studies have evaluated the association between the CYP1A1 MspI and Ile462Val polymorphisms and renal cell carcinoma (RCC) risk, but the results have been conflicting. To more precisely evaluate the potential association, we carried out a...

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Identifiers

PMID: 25630554
DOI: 10.1038/srep08108
PMCID: PMC4309971

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