Article
A genome-wide analysis of promoter-mediated phenotypic noise in Escherichia coli.
PLoS genetics - 1 Jan 2012
Silander Olin K, Nikolic Nela, Zaslaver Alon, Bren Anat, Kikoin Ilya, Alon Uri, Ackermann Martin
Abstract excerpt
Gene expression is subject to random perturbations that lead to fluctuations in the rate of protein production. As a consequence, for any given protein, genetically identical organisms living in a constant environment will contain different amounts of that particular protein, resulting in different phenotypes. This phenomenon is known as "phenotypic noise." In bacterial systems, previous studies have shown that,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.