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Article

Sequence-structure signals of 3D domain swapping in proteins.

Journal of molecular biology - 25 Jul 2003

Dehouck Yves, Biot Christophe, Gilis Dimitri, Kwasigroch Jean Marc, Rooman Marianne

Abstract excerpt

Three-dimensional domain swapping occurs when two or more identical proteins exchange identical parts of their structure to generate an oligomeric unit. It affects proteins with diverse sequences and structures, and is expected to play important roles in evolution, functional regulation and even conformational diseases. Here, we search for traces of domain swapping in the protein sequence, by means of algorithms...

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Identifiers

PMID: 12860140
DOI: 10.1016/s0022-2836(03)00614-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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