Article
Induction of vancomycin resistance in Enterococcus faecium by inhibition of transglycosylation
1 Jul 1990
Abstract excerpt
Vancomycin resistance has recently been recognized among clinical isolates of enterococci. Resistance is inducible, and associated with production of a novel 39 kDa membrane protein. The mechanism by which exposure to vancomycin, which does not penetrate the cell membrane, induces resistance is unknown. In the vancomycin resistant strain Enterococcus faecium 228, resistance was also inducible by moenomycin,...
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