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Article

The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation.

European journal of biochemistry - 15 May 1997

Brötz H, Bierbaum G, Reynolds P E, Sahl H G

Abstract excerpt

The lantibiotic mersacidin has been previously reported to interfere with bacterial peptidoglycan biosynthesis, [Brötz, H., Bierbaum, G., Markus, A., Molitor, E. & Sahl, H.-G. (1995) Antimicrob. Agents Chemother. 39, 714-719]. Here, we focus on the target reaction and describe a mersacidin-induced accumulation of UDP-N-acetylmuramoyl-pentapeptide, indicating that inhibition of peptidoglycan synthesis occurs after...

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Identifiers

PMID: 9210483
DOI: 10.1111/j.1432-1033.1997.t01-1-00193.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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