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Article

UBQ-8i polymorphism is not an independent risk factor for mild cognitive impairment and Alzheimer's disease in APOE-4 carriers.

Current Alzheimer research - 1 May 2012

Martin X Elcoroaristizabal, Martinez M Fernandez, Fernandez D Gamarra, Busto F Gomez, Alcelay L Galdos, Ferreras M J Calzada, Flores J Castro, Pancorbo M M de

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) has a complex genetic etiology, and as a result many genes have been studied to determine how they might be involved with the disease. Amyloidogenic effects have been broadly linked with familial forms of the disease, though certain genes such as UBQLN1 could also play a role in prodromal phases such as amnesic mild cognitive impairment (MCI). AIM: The aim of this study is to...

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Source

Identifiers

PMID: 22272618
DOI: 10.2174/156720512800492440

Genes

APOE
UBQLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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UBQ-8i polymorphism is not an independent risk factor for mild cognitive impairment and Alzheimer's disease in APOE-4 carriers.PMID 22272618Read ↗

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