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Article

Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.

PloS one - 1 Jan 2012

Bierau Jörgen, Bakker Jaap A, Schippers Jolanda A, Grashorn Janine A C, Lindhout Martijn, Lowe Selwyn H, Paulussen Aimée D C, Verbon Annelies

Abstract excerpt

BACKGROUND: Inosine triphosphatase (ITPase) is encoded by the polymorphic gene ITPA and maintains low intracellular levels of the inosine nucleotides ITP and dITP. The most frequently reported polymorphisms are ITPA c.94C>A (rs 1127354) and ITPA c. 124+21 A>C (rs7270101). Some nucleoside-analogue...

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Source

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Identifiers

PMID: 22272297
DOI: 10.1371/journal.pone.0030175
PMCID: PMC3260219

Genes

ITPA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22272297-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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