Article
High Prevalence of ITPA Alleles Associated with Ribavirin-Induced Hemolytic Anemia Among Mexican Population.
Annals of hepatology - 1 Jan 2000
Gonzalez-Aldaco Karina, Rebello Pinho João R, Panduro Arturo, Martinez-Lopez Erika, Gleyzer Ketti, Fierro Nora, Roman Sonia
Abstract excerpt
BACKGROUND: The prevalence of two functional polymorphisms (rs1127354 and rs7270101) of the inosine triphosphatase (ITPA) gene associated with ribavirin-induced hemolytic anemia (RIHA) during antiviral therapy for hepatitis C virus (HCV) infection varies by ethnicity. In Mexico, the distribution of these polymorphisms among Native Amerindians (NA) and admixed population (Mestizos) is unknown. This study aimed to...
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