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Article

Protective role of D-amino acid oxidase against Staphylococcus aureus infection.

Infection and immunity - 1 Apr 2012

Nakamura Hideaki, Fang Jun, Maeda Hiroshi

Abstract excerpt

D-Amino acid oxidase (DAO) is a hydrogen peroxide-generating enzyme that uses a D-amino acid as a substrate. We hypothesized that DAO may protect against bacterial infection, because hydrogen peroxide is one of the most important molecules in the antibacterial defense systems in mammals. We show here that DAO suppressed the growth of Staphylococcus aureus in a manner that depended on the concentration of DAO and...

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Source

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Identifiers

PMID: 22271930
DOI: 10.1128/IAI.06214-11
PMCID: PMC3318415

Genes

DAO
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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