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Article

Cadherin-11, a marker of the mesenchymal phenotype, regulates glioblastoma cell migration and survival in vivo.

Molecular cancer research : MCR - 1 Mar 2012

Kaur Harpreet, Phillips-Mason Polly J, Burden-Gulley Susan M, Kerstetter-Fogle Amber E, Basilion James P, Sloan Andrew E, Brady-Kalnay Susann M

Abstract excerpt

Glioblastoma multiforme (GBM) is the most malignant and lethal form of astrocytoma. The GBM patient survival time of approximately 1 year necessitates the identification of novel molecular targets and more effective therapeutics. Cadherin-11, a calcium-dependent cell-cell adhesion molecule and mesenchymal marker, plays a role in both normal tissue development and in cancer cell migration. The functional...

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Identifiers

PMID: 22267545
DOI: 10.1158/1541-7786.MCR-11-0457
PMCID: PMC3307867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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