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Article

Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines

17 Jan 2012

Abstract excerpt

Cdc42, a Rho GTPase family member, is involved in cell transformation, proliferation, survival, invasion and metastasis of human cancer cells. Overexpression of Cdc42 has been reported in several types of human cancer. However, the underlying mechanisms are not well understood. The present study showed that Cdc42 was overexpressed in 80 of 110 primary lung cancer patients, and overexpression of Cdc42 was...

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PMID: 22266952
DOI: 10.3892/ijo.2012.1336

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