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Article

Interactions and relationships of PTEN, ERG, SPINK1 and AR in castration‐resistant prostate cancer

19 Jan 2012

Abstract excerpt

AIMS: Recently, ETS-related gene (ERG) gene rearrangements, phosphatase tensin homologue (PTEN) deletions and serine protease inhibitor Kazal type 1 (SPINK1) overexpression were investigated as potential markers for molecularly subtyping prostate cancer (PCA). However, their incidence and co-association in castration-resistant PCA (CRPC) has not been characterized fully. METHODS AND RESULTS: A cohort of 59 CRPC...

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PMID: 22260502
DOI: 10.1111/j.1365-2559.2011.04116.x

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