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Article

Loss of PTEN Is Associated with Aggressive Behavior in ERG-Positive Prostate Cancer

2 Oct 2013

Abstract excerpt

BACKGROUND: The associations of ERG overexpression with clinical behavior and molecular pathways of prostate cancer are incompletely known. We assessed the association of ERG expression with AR, PTEN, SPINK1, Ki-67, and EZH2 expression levels, deletion, and mutations of chromosomal region 3p14 and TP53, and clinicopathologic variables. METHODS: The material consisted of 326 prostatectomies, 166 needle biopsies...

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PMID: 24083995
DOI: 10.1158/1055-9965.epi-13-0333-t

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Loss of PTEN Is Associated with Aggressive Behavior in ERG-Positive Prostate CancerPMID 24083995Read ↗

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