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Article

Subpopulation analysis of heteroresistance to fluoroquinolone in Mycobacterium tuberculosis isolates from Beijing, China.

Journal of clinical microbiology - 1 Apr 2012

Zhang Xiaobing, Zhao Bing, Liu Liguo, Zhu Yafang, Zhao Yanlin, Jin Qi

Abstract excerpt

The presence of heteroresistance was represented by 23% of 235 fluoroquinolone (FQ)-resistant Mycobacterium tuberculosis isolates in Beijing, China, from 2008 to 2010. The main mechanism of FQ heteroresistance is due to the segregation of a single M. tuberculosis strain in patients; the majority of isolates with multidrug-resistant tuberculosis contained a mixture of bacterial subpopulations consisting of various...

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Identifiers

PMID: 22259208
DOI: 10.1128/JCM.05793-11
PMCID: PMC3318552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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