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Article

Co-occurrence of amikacin-resistant and -susceptible Mycobacterium tuberculosis isolates in clinical samples from Beijing, China.

The Journal of antimicrobial chemotherapy - 1 Jul 2013

Zhang Xiaobing, Zhao Bing, Huang Hairong, Zhu Yafang, Peng Junping, Dai Guangming, Jiang Guanglu, Liu Liguo, Zhao Yanlin, Jin Qi

Abstract excerpt

OBJECTIVES: This study examined the phenomenon of heteroresistance in Mycobacterium tuberculosis clinical isolates obtained from retreated patients in Beijing, China between 2006 and 2011. METHODS: The iPLEX Gold assay platform was used to determine the prevalence of heteroresistance to injectable second-line drugs (amikacin, kanamycin and capreomycin) in resistant isolates. RESULTS: Heteroresistance was...

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PMID: 23539239
DOI: 10.1093/jac/dkt082

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