Article
ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity.
Cell death & disease - 19 Jan 2012
Shao Y, Aplin A E
Abstract excerpt
B-cell lymphoma 2 (Bcl-2) homology 3 (BH3)-only proteins represent a class of pro-apoptotic factors that neutralize pro-survival Bcl-2 proteins, and, in some cases, directly activate Bax. The mechanisms of control and the role of BH3-only proteins, such as Bcl-2 like protein 11 extra large and Bad are well studied. By contrast, relatively little is known about the regulation and role of Bcl-2 modifying factor...
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