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Article

HIV cell-to-cell transmission requires the production of infectious virus particles and does not proceed through env-mediated fusion pores.

Journal of virology - 1 Apr 2012

Monel Blandine, Beaumont Elodie, Vendrame Daniela, Schwartz Olivier, Brand Denys, Mammano Fabrizio

Abstract excerpt

Direct cell-to-cell transmission of human immunodeficiency virus (HIV) is a more potent and efficient means of virus propagation than infection by cell-free virus particles. The aim of this study was to determine whether cell-to-cell transmission requires the assembly of enveloped virus particles or whether nucleic acids with replication potential could translocate directly from donor to target cells through...

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Share to HIV Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to env Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 22258237
DOI: 10.1128/JVI.06478-11
PMCID: PMC3302491

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