Article
Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein
1 Mar 1994
Abstract excerpt
The matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) forms an inner coat directly underneath the lipid envelope of the virion. The outer surface of the lipid envelope surrounding the capsid is coated by the viral Env glycoproteins. We report here that the HIV-1 capsid-Env glycoprotein association is very sensitive to minor alterations in the MA protein. The results indicate that most of the MA...
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