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Article

Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C.

Gastroenterology - 1 Apr 2012

Chu Tom W, Kulkarni Rohit, Gane Edward J, Roberts Stuart K, Stedman Catherine, Angus Peter W, Ritchie Brett, Lu Xiao-Yu, Ipe David, Lopatin Uri, Germer Soren, Iglesias Victor A, Elston Robert, Smith Patrick F, Shulman Nancy S

Abstract excerpt

BACKGROUND & AIMS: Although interleukin 28B (interferon, lambda 3) (IL28B) genotype affects the response of patients with chronic hepatitis C to peginterferon and ribavirin, little is known regarding its effect on response to direct-acting antivirals in interferon-free combinations. We analyzed the effects of IL28B genotype on the viral kinetic (VK) response to an interferon-free combination of the nucleoside...

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Identifiers

PMID: 22248659
DOI: 10.1053/j.gastro.2011.12.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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