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Article

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease.

PloS one - 1 Jan 2012

Buizza Laura, Cenini Giovanna, Lanni Cristina, Ferrari-Toninelli Giulia, Prandelli Chiara, Govoni Stefano, Buoso Erica, Racchi Marco, Barcikowska Maria, Styczynska Maria, Szybinska Aleksandra, Butterfield David Allan, Memo Maurizio, Uberti Daniela

Abstract excerpt

In order to study oxidative stress in peripheral cells of Alzheimer's disease (AD) patients, immortalized lymphocytes derived from two peculiar cohorts of patients, referring to early onset AD (EOSAD) and subjects harboured AD related mutation (ADmut), were used. Oxidative stress was evaluated measuring i) the typical oxidative markers, such as HNE Michel adducts, 3 Nitro-Tyrosine residues and protein carbonyl on...

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Identifiers

PMID: 22242180
DOI: 10.1371/journal.pone.0029789
PMCID: PMC3252333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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