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Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles

12 Jan 2012

Abstract excerpt

BACKGROUND: Recently, we used cell-free assays to demonstrate the toxic effects of complex mixtures of organic extracts from urban air particles (PM2.5) collected in four localities of the Czech Republic (Ostrava-Bartovice, Ostrava-Poruba, Karvina and Trebon) which differed in the extent and sources of air pollution. To obtain further insight into the biological mechanisms of action of the extractable organic...

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PMID: 22239852
DOI: 10.1186/1743-8977-9-1

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