Article
Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
Journal of human genetics - 1 Mar 2012
Inoue Hiroki, Mashimo Yoichi, Funamizu Makiko, Yonekura Shuji, Horiguchi Shigetoshi, Shimojo Naoki, Kohno Yoichi, Okamoto Yoshitaka, Hata Akira, Suzuki Yoichi
Abstract excerpt
Matrix metalloproteinase 9 (MMP9) gene has been shown to be involved in the pathogenesis of allergic rhinitis (AR) and asthma. Previous studies suggested that single-nucleotide polymorphisms (SNPs) of the MMP9 gene conferred a risk for childhood asthma. However, whether the SNPs confer a risk for AR has not been previously investigated. The objective of this study was to investigate whether SNPs of the MMP9 gene...
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