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Article

Centrifugation assay for measuring adhesion of serially passaged bovine chondrocytes to polystyrene surfaces.

Tissue engineering. Part C, Methods - 1 Jul 2012

Kaplan David S, Hitchins Victoria M, Vegella Thomas J, Malinauskas Richard A, Ferlin Kimberly M, Fisher John P, Frondoza Carmelita G

Abstract excerpt

A major obstacle in chondrocyte-based therapy for cartilage repair is the limited availability of cells that maintain their original phenotype. Propagation of chondrocytes as monolayer cultures on polystyrene surfaces is used extensively for amplifying cell numbers. However, chondrocytes undergo a phenotypic shift when propagated in this manner and display characteristics of more adherent fibroblastic cells....

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Identifiers

PMID: 22235797
DOI: 10.1089/ten.TEC.2011.0043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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