Article
Acute respiratory distress syndrome induced by a swine 2009 H1N1 variant in mice.
PloS one - 1 Jan 2012
Zhang Yi, Sun Honglei, Fan Lihong, Ma Yuan, Sun Yipeng, Pu Juan, Yang Jun, Qiao Jian, Ma Guangpeng, Liu Jinhua
Abstract excerpt
BACKGROUND: Acute respiratory distress syndrome (ARDS) induced by pandemic 2009 H1N1 influenza virus has been widely reported and was considered the main cause of death in critically ill patients with 2009 H1N1 infection. However, no animal model has been developed for ARDS caused by infection with 2009 H1N1 virus. Here, we present a mouse model of ARDS induced by 2009 H1N1 virus. METHODOLOGY PRINCIPAL FINDINGS:...
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