Article
Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.
Carcinogenesis - 1 Mar 2012
Shen Jie, Wang Dan, Gregory Steven R, Medico Leonard, Hu Qiang, Yan Li, Odunsi Kunle, Lele Shashikant B, Ambrosone Christine B, Liu Song, Zhao Hua
Abstract excerpt
Interindividual variations of microRNA expression are likely to influence the expression of microRNA target genes and, therefore, contribute to phenotypic differences in humans, including cancer susceptibility. Whether microRNA expression variation has any role in ovarian cancer development is still unknown. Here, we evaluated microRNA expression profiles in lymphoblastoid cell lines from 74 women with familial...
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