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Article

Clinically relevant microRNAs in ovarian cancer.

Molecular cancer research : MCR - 1 Mar 2015

Zhang Shu, Lu Zhen, Unruh Anna K, Ivan Cristina, Baggerly Keith A, Calin George A, Li Zongfang, Bast Robert C, Le Xiao-Feng

Abstract excerpt

microRNAs (miRNAs/miRs) belong to a class of small noncoding RNAs that can negatively regulate messenger RNA (mRNA) expression of target genes. miRNAs are involved in multiple aspects of ovarian cancer cell dysfunction and the phenotype of ovarian cancer cells can be modified by targeting miRNA expression. miRNA profiling has detected a number of candidate miRNAs with the potential to regulate many important...

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Share to Ovarian Neoplasms
Share to RNA, Messenger
Share to 3' Untranslated Regions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 25304686
DOI: 10.1158/1541-7786.MCR-14-0424
PMCID: PMC4369176

Genes

BRCA1
DIRAS3
MUC16
WFDC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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