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Effects of Paraquat and Capsaicin on the Expression of Genes Related to Inflammatory, Immune Responses and Cell Death in Immortalized Human HaCat Keratinocytes

1 Oct 2011

Abstract excerpt

The present experiments were aimed to characterize in immortalized human HaCat keratinocytes the gene expression induced by paraquat and capsaicin, two agents known to induce cell death or to affect inflammatory and pain pathways, respectively. In particular, the following set of genes were analysed by qRealtime PCR: CXCL10,CXCL11, IL-10 (inflammatory and immune responses), TP73, BCL2, (apoptotic and...

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PMID: 22230393
DOI: 10.1177/039463201102400405

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