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Article

Xanthine oxidase-generated hydrogen peroxide is a consequence, not a mediator of cell death.

The FEBS journal - 1 Mar 2012

Czupryna Julie, Tsourkas Andrew

Abstract excerpt

Oxidative stress has been associated with a wide range of diseases including atherosclerosis, cancer and Alzheimer's disease. When present in excessive concentrations, reactive oxygen species (ROS) can cause deleterious effects. This has led to the notion that the anticancer effects of various chemotherapeutics may be mediated, at least in part, by an increase in ROS. To investigate the role of xanthine oxidase...

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Identifiers

PMID: 22230240
DOI: 10.1111/j.1742-4658.2012.08475.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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