Article
ApoE ε4 and IL-6-174G/C Polymorphism may Lead to Early Onset of Alzheimer's Disease with Atypical Presentation.
Neurology India - 1 Jan 2000
Chakraborty Sayantan, Joardar Anindita, Roy Sarnava, Gangopadhyay Gautam, Biswas Atanu
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) is the most common cause of dementia. Although genetic mutations are known in rare familial form, exact cause of neurodegeneration in sporadic AD is still unknown. While ApoE ε4 and IL-6 C-174G/C patterns have been found to increase the risk of AD in Caucasians, the results are inconsistent in other ethnic groups. OBJECTIVE: The aim of this study was to evaluate the effect of...
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