Article
Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia.
Behavioral and brain functions : BBF - 6 Jan 2012
Uezato Akihito, Kimura-Sato Junko, Yamamoto Naoki, Iijima Yoshimi, Kunugi Hiroshi, Nishikawa Toru
Abstract excerpt
BACKGROUND: The synapse-associated protein 97 gene (SAP97) encodes a regulatory scaffold protein for the localization of L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA), kainate and N-methyl-D-aspartate (NMDA) type glutamate receptors. We have recently demonstrated nominally significant associations between SAP97 gene and schizophrenia among Japanese males. The present study aimed to replicate...
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