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PLA2G6 mutations in PARK14-linked young-onset parkinsonism and sporadic Parkinson's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2012

Lu Chin-Song, Lai Szu-Chia, Wu Ruey-Meei, Weng Yi-Hsin, Huang Chia-Ling, Chen Rou-Shayn, Chang Hsiu-Chen, Wu-Chou Yah-Huei, Yeh Tu-Hsueh

Abstract excerpt

Mutations of PLA2G6 gene have been lately proposed to be the causative gene for PARK14 in patients with autosomal recessive young-onset parkinsonism (YOPD). The role of PLA2G6 mutations as a risk factor for Parkinson's disease is not clear. To study the PLA2G6 mutations in PARK14-linked patients and its association with the onset of sporadic Parkinson's disease (sPD), sequencing and gene dosage analyses were...

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PMID: 22213678
DOI: 10.1002/ajmg.b.32012

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PRKN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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