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Article

Alveolar epithelial type II cells and their microenvironment in the caveolin-1-deficient mouse.

Anatomical record (Hoboken, N.J. : 2007) - 1 Feb 2012

Jung Kristina, Schlenz Heike, Krasteva Gabriela, Mühlfeld Christian

Abstract excerpt

Caveolin-1 (Cav-1) is highly expressed in alveolar epithelial type I (AE1) and endothelial cells of the alveolar region of the lung. Interestingly, alveolar epithelial type II (AE2) cells that are progenitors of the AE1 cells do not express Cav-1. We investigated whether genetic Cav-1 deficiency alters the phenotype of AE2 cells and their microenvironment using stereology. Total number, mean volume, and...

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PMID: 22213628
DOI: 10.1002/ar.21543

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