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Article

Cavin1; a regulator of lung function and macrophage phenotype.

PloS one - 1 Jan 2013

Govender Praveen, Romero Freddy, Shah Dilip, Paez Jesus, Ding Shi-Ying, Liu Libin, Gower Adam, Baez Elizabeth, Aly Sherif Shawky, Pilch Paul, Summer Ross

Abstract excerpt

Caveolae are cell membrane invaginations that are highly abundant in adipose tissue, endothelial cells and the lung. The formation of caveolae is dependent on the expression of various structural proteins that serve as scaffolding for these membrane invaginations. Cavin1 is a newly identified structural protein whose deficiency in mice leads to loss of caveolae formation and to development of a lipodystrophic...

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Identifiers

PMID: 23634221
DOI: 10.1371/journal.pone.0062045
PMCID: PMC3636273

Genes

CCL2
CXCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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