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Article

Presence of cytogenetic abnormalities in Spitz naevi: a diagnostic challenge for fluorescence in‐situ hybridization analysis

23 Dec 2011

Abstract excerpt

AIMS: Spitz naevi are difficult to diagnose, because of significant overlap with melanomas. It has been recently demonstrated that the LSI RREB1(6p25)/LSI MYB(6q23)/LSI CCND1(11q13)/CEP6 fluorescence in-situ hybridization (FISH) assay is a reliable tool with which to distinguish benign naevi and melanomas. Little is known about its diagnostic usefulness in Spitz naevi. METHODS AND RESULTS: We investigated 51...

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Identifiers

PMID: 22211292
DOI: 10.1111/j.1365-2559.2011.04087.x

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