Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bmi-1 induces radioresistance in MCF-7 mammary carcinoma cells

30 Dec 2011

Abstract excerpt

Bmi-1, a member of the polycomb family, it is involved in self renewal of stem cells and functions as an oncogene in many malignant human cancer types. Recent studies have demonstrated that Bmi-1 is a predictive factor for poor patient prognosis. However, the underlying mechanisms of radioresistance mediated by Bmi-1 are poorly understood. In this study, the dose-survival relationship was analyzed using a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to Plant Genetic and Mutation Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22209830
DOI: 10.3892/or.2011.1615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bmi-1 induces radioresistance in MCF-7 mammary carcinoma cellsPMID 22209830Read ↗

Enhancing Chemotherapy Response with Bmi-1 Silencing in Ovarian CancerSemantic proximity Read ↗

BMI-1, a promising therapeutic target for human cancerSemantic proximity Read ↗

BMI1 as a novel target for drug discovery in cancerSemantic proximity Read ↗

Overexpression of BMI-1 Promotes Cell Growth and Resistance to Cisplatin Treatment in OsteosarcomaSemantic proximity Read ↗

SNAI2-mediated direct repression of <i>BIM</i> protects rhabdomyosarcoma from ionizing radiationSemantic proximity Read ↗

BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cellsSemantic proximity Read ↗

Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells.Semantic proximity Read ↗

BMI ‐1 promotes breast cancer proliferation and metastasis through different mechanisms in different subtypesSemantic proximity Read ↗

Silencing of Bmi-1 Gene Enhances Chemotherapy Sensitivity in Human Glioblastoma CellsSemantic proximity Read ↗

Radioprotective Effects of Bmi-1 Involve Epigenetic Silencing of Oxidase Genes and Enhanced DNA Repair in Normal Human KeratinocytesSemantic proximity Read ↗

Suppression of FOXM1 Sensitizes Human Cancer Cells to Cell Death Induced by DNA-DamageSemantic proximity Read ↗

Downregulation of Mitochondrial Single Stranded DNA Binding Protein (SSBP1) Induces Mitochondrial Dysfunction and Increases the Radiosensitivity in Non-Small Cell Lung Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.