Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone.

doi:10.1371/journal.pone.0028850

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Article

Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone.

PloS one - 1 Jan 2011

Hiller N Luisa, Eutsey Rory A, Powell Evan, Earl Joshua P, Janto Benjamin, Martin Darren P, Dawid Suzanne, Ahmed Azad, Longwell Mark J, Dahlgren Margaret E, Ezzo Suzanne, Tettelin Herve, Daugherty Sean C, Mitchell Timothy J, Hillman Todd A, Buchinsky Farrel J, Tomasz Alexander, de Lencastre Herminia, Sá-Leão Raquel, Post J Christopher, Hu Fen Z, Ehrlich Garth D

Abstract excerpt

We report on the comparative genomics and characterization of the virulence phenotypes of four S. pneumoniae strains that belong to the multidrug resistant clone PMEN1 (Spain(23F) ST81). Strains SV35-T23 and SV36-T3 were recovered in 1996 from the nasopharynx of patients at an AIDS hospice in New York. Strain SV36-T3 expressed capsule type 3 which is unusual for this clone and represents the product of an in vivo...

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PMID: 22205975
DOI: 10.1371/journal.pone.0028850
PMCID: PMC3242761

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