Article
Comparative "-omics" in Mycoplasma pneumoniae Clinical Isolates Reveals Key Virulence Factors.
PloS one - 1 Jan 2015
Lluch-Senar Maria, Cozzuto Luca, Cano Jaime, Delgado Javier, Llórens-Rico Verónica, Pereyre Sabine, Bebear Cécile, Serrano Luis
Abstract excerpt
The human respiratory tract pathogen M. pneumoniae is one of the best characterized minimal bacterium. Until now, two main groups of clinical isolates of this bacterium have been described (types 1 and 2), differing in the sequence of the P1 adhesin gene. Here, we have sequenced the genomes of 23 clinical isolates of M. pneumoniae. Studying SNPs, non-synonymous mutations, indels and genome rearrangements of these...
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