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<i>Hydroxysteroid (17-β) Dehydrogenase 1</i> Is Dysregulated by <i>Mir-210</i> and <i>Mir-518c</i> That Are Aberrantly Expressed in Preeclamptic Placentas

28 Dec 2011

Abstract excerpt

In this study, to search for novel preeclampsia (PE) biomarkers, we focused on microRNA expression and function in the human placenta complicated with PE. By comprehensive analyses of microRNA expression, we identified 22 microRNAs significantly upregulated in preeclamptic placentas, 5 of which were predicted in silico to commonly target the mRNA encoding hydroxysteroid (17-β) dehydrogenase 1 (HSD17B1), a...

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PMID: 22203747
DOI: 10.1161/hypertensionaha.111.180232

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