MicroRNA‑144‑3p may participate in the pathogenesis of preeclampsia by targeting Cox‑2

Abstract excerpt

Preeclampsia remains a major cause of maternal mortality and morbidity worldwide. It is generally accepted that the development of the placenta, including spiral artery remodelling, normal trophoblast cells function and maternal‑fetal inflammation‑immune interactions, is critical for the pathogenesis of preeclampsia. Several investigations have demonstrated that microRNAs (miRNAs/miRs) in the placenta may be...

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