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Article

SIRTUIN 1 gene polymorphisms are associated with cholesterol metabolism and coronary artery calcification in Japanese hemodialysis patients.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation - 1 Jan 2012

Shimoyama Yasuhiko, Mitsuda Yoko, Tsuruta Yoshinari, Suzuki Koji, Hamajima Nobuyuki, Niwa Toshimitsu

Abstract excerpt

OBJECTIVES: Sirtuin 1 (SIRT1), a longevity gene, protects cells against oxidative and genotoxic stress. This study aimed to investigate the association of SIRT 1 gene single-nucleotide polymorphisms, namely, rs7895833, rs7069102, and rs2273773 with lipid profiles and coronary artery calcification score in 219 Japanese hemodialysis (HD) patients. METHODS: Genotyping of these polymorphisms was performed using...

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Source

Identifiers

PMID: 22200427
DOI: 10.1053/j.jrn.2011.10.025

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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