Article
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease.
Experimental neurology - 1 Mar 1999
Miller G W, Erickson J D, Perez J T, Penland S N, Mash D C, Rye D B, Levey A I
Abstract excerpt
The vesicular monoamine transporter (VMAT2) has been suggested to be an excellent marker of presynaptic dopaminergic nerve terminals in the striatum of Parkinson's disease patients based on its high level of expression and insensitivity to drugs used to treat the disease. Previous in vivo imaging and postmortem binding studies have detected a loss in striatal VMAT2 binding in Parkinson's diseased (PD) brain;...
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