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Article

[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].

Sheng li xue bao : [Acta physiologica Sinica] - 25 Dec 2011

Wu Ting, Huang Xiao-Hua

Abstract excerpt

Multiple endocrine neoplasia type 1 (MEN1) is a dominantly inherited tumor syndrome characterized by development of various combinations of tumors in multiple endocrine glands, including the pituitary, parathyroid or pancreas. MEN1 results from mutations in tumor suppressor gene Men1, which encodes nuclear protein menin. Menin has been shown to preferentially repress cell proliferation in endocrine tissues...

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Source

Identifiers

PMID: 22193451

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].PMID 22193451Read ↗

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Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localizationSemantic proximity Read ↗

Dynamic Epigenetic Regulation by Menin During Pancreatic Islet Tumor FormationSemantic proximity Read ↗

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumorsSemantic proximity Read ↗

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